Using spatial analysis to estimate depopulation for Native American populations in northeastern North America, AD 1616–1645

0278-4165/$ see front matter 2011 Elsevier Inc. A doi:10.1016/j.jaa.2011.10.004 ⇑ Corresponding author. E-mail addresses: [email protected] (E.E. Jones), d DeWitte). Eight years ago, Ramenofsky et al. (2003) characterized the discussion of the impact of Old World diseases on Native American populations as almost exclusively historical in nature. They specifically argued for the application of more evolutionary, genetic, and epidemiological theory to research into this topic. We agree with their assessment and further suggest that such research would greatly benefit from spatial analyses of disease spread as well. Using trend surface analysis of existing ethnohistorical and archaeological data pertaining to population sizes and disease events, we examine the spatiotemporal dimensions of 17th century depopulation in northeastern North America. The subsequent results allow us to predict possible depopulation rates for populations with very little demographic data. Further, our use of biological, historical, and cultural data to interpret the results represents an attempt to provide a more complex explanation for the variability in cultural survivability across the region and several possible avenues for productive future research. We believe research like this can significantly improve our understanding of how Old World diseases affected historic Native American populations and cultures and continue to impact them today. 2011 Elsevier Inc. All rights reserved.